Dr Paayal Agrawaal – Fertility Consultant

PESA/TESE

Infertility and IVF - PESA/TESE

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What is PESA/TESE?

PESA (Percutaneous Epididymal Sperm Aspiration) and TESE (Testicular Sperm Extraction) are surgical sperm retrieval techniques used in assisted reproductive treatments like IVF, primarily for men who have no sperm in their ejaculate (azoospermia) due to a blockage or testicular failure.

  • PESA is a minimally invasive procedure where a fine needle is inserted into the epididymis (a small tube where sperm is stored after being produced in the testicles) to aspirate sperm. It is usually done under local anesthesia and is often used in cases of obstructive azoospermia—where sperm is produced but can’t be ejaculated due to a blockage (e.g., vasectomy or congenital absence of the vas deferens).

  • TESE involves making a small incision in the testicle to extract a small amount of tissue, from which sperm are isolated. TESE is used when PESA doesn’t yield sperm or in cases of non-obstructive azoospermia, where sperm production is severely impaired.

Both procedures are typically followed by ICSI (Intracytoplasmic Sperm Injection), where a single sperm is injected directly into an egg to achieve fertilization. These techniques offer a chance of biological parenthood to men with severe male infertility.

Benefits of PESA/TESE Treatment